Anti-pan ASIC (extracellular) Antibody ASC-031 from Alomone Labs, Ltd.

Description

Alomone Labs is pleased to offer an antibody directed against an epitope of rat ASIC1. The antibody recognizes ASIC1 through ASIC4. Anti-pan ASIC (extracellular) Antibody (#ASC-031) can be used in western blot, immunohistochemistry and immunocytochemistry in living cells. It has been designed to recognize all ASIC channels from rat, human and mouse samples

Product Specs
ItemAnti-pan ASIC (extracellular) Antibody
CompanyAlomone Labs, Ltd.
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberASC-031
Quantity1 X 25 mcl, 1 X 50 mcl, 1 X 0.2 ml
ApplicationsICC, IF, IHC, LCI, WB
Conjugate/TagUnconjugated
FormatReconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3., Lyophilized Powder
ReactivityHuman (Tested);Mouse (Tested);Rat (Tested)
HostRabbit
Domain/Region/Terminusextracellular
Brand/TrademarkAlomone Labs Ltd
ClonalityPolyclonal
Concentration08 mg/ml
PurityAffinity purified on immobilized antigen
IsotypeIgG
ImmunogenSynthetic peptide
NCBI Full Gene Nameacid sensing ion channel subunit 1
NCBI Gene AliasesAccn2
TargetASIC Channels (ASIC1, ASIC2, ASIC3, ASIC4)
ValidationAs per applications, See images, contact for clarifications
pH RangepH 7.4

Specifications/Features

starting price for North American orders, for exact pricing view product page

Sequence

(C)TRYGKELSMVKIPSK, corresponding to amino acid residues 368-382 of rat ASIC1

Add to Compare List

Alomone Labs, Ltd.

PO Box 4287

Jerusalem 91042

Israel

Phone: +972-2-587-2202
+972-2-587-1101

Company Profile

Website: http://www.alomone.com/

(1) The method of Yiqi Yangyin Tongluo can attenuate the pyroptosis of rheumatoid arthritis chondrocytes through the ASIC1a/NLRP3 signaling pathwayAnnals of translational medicineFebruary 1, 2022Zhao Y, Chen Y, Wang Z, Peng C, Li Q, Wu J, Wang L, Liu D, Yue Y, Qing Q, et al.

(2) A variant of ASIC2 mediates sodium retention in nephrotic syndromeJCI insightAugust 9, 2021Fila M, Sassi A, Brideau G, Cheval L, Morla L, Houillier P, Walter C, Gennaoui M, Collignon L, Keck M, et al.

(3) Upregulation of spinal ASIC1 by miR-485 mediates enterodynia in adult offspring rats with prenatal maternal stressCNS neuroscience & therapeuticsFebruary 1, 2021Xu X, Li YC, Wu YY, Xu YC, Weng RX, Wang CL, Zhang PA, Zhang Y, Xu GY.

(4) ASIC1a activation induces calcium-dependent apoptosis of BMSCs under conditions that mimic the acidic microenvironment of the degenerated intervertebral discBioscience reportsNovember 29, 2019Cai F, Hong X, Tang X, Liu NC, Wang F, Zhu L, Xie XH, Xie ZY, Wu XT.

(5) PI3-kinase/Akt pathway-regulated membrane transportation of acid-sensing ion channel 1a/Calcium ion influx/endoplasmic reticulum stress activation on PDGF-induced HSC ActivationJournal of cellular and molecular medicineJune 1, 2019Zuo L, Zhu Y, Hu L, Liu Y, Wang Y, Hu Y, Wang H, Pan X, Li K, Du N, et al.

(6) Interleukin-1β and tumor necrosis factor-α augment acidosis-induced rat articular chondrocyte apoptosis via nuclear factor-kappaB-dependent upregulation of ASIC1a channelBiochimica et biophysica acta. Molecular basis of diseaseJanuary 1, 2018Zhou RP, Dai BB, Xie YY, Wu XS, Wang ZS, Li Y, Wang ZQ, Zu SQ, Ge JF, Chen FH.

(7) ASIC1a Promotes Acid-Induced Autophagy in Rat Articular Chondrocytes through the AMPK/FoxO3a PathwayInternational journal of molecular sciencesOctober 11, 2017Dai B, Zhu F, Chen Y, Zhou R, Wang Z, Xie Y, Wu X, Zu S, Li G, Ge J, et al.

Be the First to Write a Review!

IHC